Hepatic Profile

More About Hepatic Profile

Albumin, Globulin, Protein
Albumin, Globulin and Total Protein are used to screen for liver disonders and nutritional deficiencies. Their levels may also be altered in Kidney disease.

Alkaline Phosphatase (ALP)
Alkaline phosphatase is an enzyme found in high levels in bone and liver.
This is the reason it is used to screen for or monitor, treatment for a liver or bone disorder and is part of the liver function test profile.

Gamma GT
Gamma GT is used to screen for liver disease or alcohol abuse; and to help your doctor tell whether a raised concentration of alkaline phosphatase (ALP) in the bloodstream is due to liver or bone disease.

Liver function tests
Aspartate aminotransferase (AST), Alanine Aminotransferase (ALT), and bilirubin
These tests together as a group are refer to them as 'liver function tests'.
They detect liver damage or an inherited liver disorder.

Total bilirubin
When red blood cells are broken down the pigment giving them their characteristic red colour, haemoglobin, (whose role is to carry oxygen to the tissues) is converted to unconjugated bilirubin. Only small amounts of bilirubin are normally present in the blood. In the liver, each unconjugated bilirubin molecule has a sugar molecule attached to it to form water soluble conjugated bilirubin. This is secreted into bile and carried to the intestine where bacteria break it down, eventually producing the brown pigment that colours normal stools. This metabolic process taking place in the liver is the reason that bilirubin can be used as a marker for liver disease such as cirrhosis.

Alkaline Phosphatase (ALT)
Alkaline phosphatase is an enzyme found in high levels in bone and liver.
This is the reason it is used to screen for or monitor, treatment for a liver or bone disorder and is part of the liver function test profile.

Lactate dehydrogenase (LDH)
Lactate dehydrogenase is expressed extensively in body tissues such as blood cells and heart muscle. Because it is released during tissue damage, it is a marker of common injuries and disease such as heart failure. There are five types of LDH that are distributed differentially in the human body. Even though the most common test measures all isoforms together, if a patient has high levels, measuring the percentage of each one might be ordered from the doctor in order to dermite the site of damage.

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